A map of cell type-specific auxin responses

Bargmann, Bastiaan O and Vanneste, Steffen and Krouk, Gabriel and Nawy, Tal and Efroni,, Idan and Shani, Eilon and Choe, Goh and Friml, Jiří and Bergmann, Dominique C and Estelle, Mark and Birnbaum, Kenneth D (2013) A map of cell type-specific auxin responses. Molecular Systems Biology, 9 (1). Article number: 688 . ISSN 1744-4292

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Official URL: http://dx.doi.org/10.1038/msb.2013.40


In plants, changes in local auxin concentrations can trigger a range of developmental processes as distinct tissues respond differently to the same auxin stimulus. However, little is known about how auxin is interpreted by individual cell types. We performed a transcriptomic analysis of responses to auxin within four distinct tissues of the Arabidopsis thaliana root and demonstrate that different cell types show competence for discrete responses. The majority of auxin-responsive genes displayed a spatial bias in their induction or repression. The novel data set was used to examine how auxin influences tissue-specific transcriptional regulation of cell-identity markers. Additionally, the data were used in combination with spatial expression maps of the root to plot a transcriptomic auxin-response gradient across the apical and basal meristem. The readout revealed a strong correlation for thousands of genes between the relative response to auxin and expression along the longitudinal axis of the root. This data set and comparative analysis provide a transcriptome-level spatial breakdown of the response to auxin within an organ where this hormone mediates many aspects of development.

Item Type: Article
DOI: 10.1038/msb.2013.40
Subjects: 500 Science > 580 Plants > 581 Botany
Research Group: Friml Group
SWORD Depositor: Sword Import User
Depositing User: Sword Import User
Date Deposited: 29 Jan 2018 10:33
Last Modified: 29 Jan 2018 10:33
URI: https://repository.ist.ac.at/id/eprint/936

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