Cell polarity and patterning by PIN trafficking through early endosomal compartments in arabidopsis thaliana

Tanaka, Hirokazu and Kitakura, Saeko and Rakusová, Hana and Uemura, Tomohiro and Feraru, Mugurel I and De Rycke, Riet M U and Robert, Stéphanie and Kakimoto, Tatsuo and Friml, Jiří (2013) Cell polarity and patterning by PIN trafficking through early endosomal compartments in arabidopsis thaliana. PLoS Genetics, 9 (5). Article No. http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.e1003540. ISSN 1553-7404

[img] Text
journal.pgen.1003540.pdf - Published Version
Available under License Creative Commons Attribution.
[IST-2016-411-v1+1]
Download (3723Kb)
Official URL: http://journals.plos.org/plosgenetics/article?id=1...

Abstract

PIN-FORMED (PIN) proteins localize asymmetrically at the plasma membrane and mediate intercellular polar transport of the plant hormone auxin that is crucial for a multitude of developmental processes in plants. PIN localization is under extensive control by environmental or developmental cues, but mechanisms regulating PIN localization are not fully understood. Here we show that early endosomal components ARF GEF BEN1 and newly identified Sec1/Munc18 family protein BEN2 are involved in distinct steps of early endosomal trafficking. BEN1 and BEN2 are collectively required for polar PIN localization, for their dynamic repolarization, and consequently for auxin activity gradient formation and auxin-related developmental processes including embryonic patterning, organogenesis, and vasculature venation patterning. These results show that early endosomal trafficking is crucial for cell polarity and auxin-dependent regulation of plant architecture.

Item Type: Article
DOI: 10.1371/journal.pgen.1003540
Uncontrolled Keywords: Endocytosis, cell migration, morphogenesis, nonhuman, controlled study, Cell polarity, Organogenesis, Endosome, Arabidopsis thaliana, cell compartmentalization, developmental stage, embryo pattern formation, plant root, protein localization, regulatory mechanism, repolarization, vasculature venation patterning
Subjects: 500 Science > 570 Life sciences; biology
Research Group: Friml Group
SWORD Depositor: Sword Import User
Depositing User: Sword Import User
Date Deposited: 04 Jan 2016 16:03
Last Modified: 05 Sep 2017 14:39
URI: https://repository.ist.ac.at/id/eprint/411

Actions (login required)

View Item View Item